Gibco™ CD OptiCHO™ Medium

Supplier:  Gibco™ 12681011

Catalog No. 50-591-551

Description

CD OptiCHO™ medium is specifically designed to offer high performance and yield with recombinant CHO cells in a chemically defined fed-batch environment. The protein-free, animal origin free formulation is designed to provide consistency and reduces the need to screen for adventitious agents. CD OptiCHO™ medium builds on Gibco™ CD CHO’s legacy of consistent cell growth and titers, while offering up to 40% better titer and cell growth over select competitors. Thanks to its low osmolality and advanced CHO CD EfficientFeed™ Liquid Nutrient Supplement Kit feeding options, CD OptiCHO™ medium is capable of gaining 2-5 fold increases in fed-batch productivity over batch culture.

When to Use CD OptiCHO™ Medium

You are using a transfected CHO cell line other than CHO K1, GS CHO or CHO-S™ cell lines

Optimization of feeding strategies will be part of your base medium selection testing in an effort to maximize productivity

Your CHO cell line is finicky, i.e. hard to grow or adapt

When to Consider Another Gibco™ Medium

Consider CD FortiCHO™ medium when:

The cell line you are using is a transfected CHO K1, GS CHO or CHO-S™ cell line

Maximum batch culture cell densities and protein titers are needed

You have time to adapt cells into a new medium in an effort to maximize titers

Cell health at harvest is a priority for downstream processing

Consider CD CHO medium when:

Your GS CHO cells are recommended to be grown in CD CHO medium

Your cells have been successfully cultured in CD CHO medium in the past and your process is nearing a regulatory filing (DMF available)

Consider CD DG44 medium when:

You use parental DG44 or DXB11 CHO cells (dhfr-)

Dry Media Formulations
Gibco™ liquid media are available in an AGT™ (Advanced Granulation Technology) dry media format that is designed to provide increased consistency and productivity across all stages of production from development to commercial manufacturing. AGT™ media are manufactured animal origin-free with the same complete, serum-free, protein-free, chemically-defined formulation and performance as their liquid media counterparts.

Design Your Own Media Specific to Your Needs
Whether it’s a bench-level experiment or large scale biomanufacturing process, we offer specialized formats, packaging, and quality levels specific to your needs. With Gibco™ cGMP Media Custom Services you can put the manufacturing power and years of technical experience of our R&D and Bioproduction Application Specialists to work for you.

Specifications

• Content And Storage: Store in refrigerator (2–8°C) and protect from light.
• Classification: Animal Origin-free, Chemically-defined, Protein-free, Serum-free
• Culture Type: Suspension Cell Culture
• Product Type: CD OptiCHO Medium
• With Additives: Sodium Pyruvate, Sodium Bicarbonate
• Endotoxin Level: Low
• Green Features: Sustainable packaging
• Product Line: Gibco™
• Shipping Condition: Room Temperature

• Cell Line: CHO
• Concentration: 1 X
• Form: Liquid
• Serum Level: Serum-free
• Without Additives: No Glutamine, No Phenol Red
• Format: Bottle
• Included Antibiotics: No antibiotics
• Quantity: 1 L
• Species: Hamster