Thermo Scientific Chemicals Sulfanilamide 98%

Description

Sulfanilamide, CAS # 63-74-1, is an organic sulfur compound that shows antibacterial activities.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Sulfanilamide is an organic sulfur compound with antibacterial properties that are structurally similar to the p-aminobenzoic acid (PABA)
• It also has a competitive inhibitory capacity against dihydropteroate synthetases blocking the synthesis of folic acid
• Sulfanilamide competes with PABA for the bacterial enzyme dihydropteroate synthase preventing, the incorporation of PABA into dihydrofolic acid, an immediate precursor of folic acid. This culminates in the inhibition of the bacterial folic acid synthesis and also the de novo synthesis of purines and pyrimidines, resulting in cell growth arrest and cell death.

Applications

• This compound shows antibacterial activity against different species, including gram-positive, gram-negative, and Chlamydia
• In chemical reactions, this compound can act as an intermediate for the preparation of 2,6-disubstituted anilines by electrophilic substitution
• Sulfanilamide shows inhibitory activity against the enzyme, carbonic anhydrase.

Specifications

Chemical Identifiers

• CAS: 63-74-1
• Molecular Formula: C6H8N2O2S
• Molecular Weight (g/mol): 172.202
• MDL Number: MFCD00007939
• InChI Key: FDDDEECHVMSUSB-UHFFFAOYSA-N
• Synonym: 4-Aminobenzenesulfonamide
• PubChem CID: 5333
• ChEBI: CHEBI:45373
• IUPAC Name: 4-aminobenzenesulfonamide
• SMILES: C1=CC(=CC=C1N)S(=O)(=O)N

• Type: Sulfanilamide
• Physical Form: Crystalline Powder
• Melting Point: 163.0°C to 167.0°C
• Infrared Spectrum: Authentic
• Assay Percent Range: 98%
• Loss on Drying: 0.5% max. (1 g, 105°C)
• Linear Formula: 4-(H₂N)C₆H₄SO₂NH₂
• Beilstein: 14, 698
• Packaging: Plastic Bottle
• Merck Index: 15, 9057
• Solubility Information: Solubility in water: 7.5g/L (20°C).
• Formula Weight: 172.2
• Percent Purity: 98%
• Color: White
• Quantity: 500 g
• Chemical Name or Material: Sulfanilamide, 98%

Safety and Handling

Hazard Category	Warning
Hazard Statement	GHS H Statement: Causes skin irritation. May cause respiratory irritation. Causes serious eye irritation.
Precautionary Statement	GHS P Statement: Avoid breathing dust/fume/gas/mist/vapors/spray. IF ON SKIN: Wash with plenty of soap and water. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. WARNING: The information provided on this web site was developed in compliance with European Union (EU) regulations and is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling and use. It is not to be considered as either a warranty or quality specification.
EINECSNumber	200-563-4
RTECSNumber	WO8400000
TSCA	TSCA

SDS

RUO – Research Use Only