Thermo Scientific Chromatography Vials and Closures Buying Guide
Maximizing productivity and achieving reproducible results in chromatography requires a fully optimized workflow from sample through assay. With that in mind, the Thermo Scientific™ SureSTART™ portfolio supports sample security and integrity with a variety of products to fit your lab and budget.
Continue reading to learn more about vials, septa, closures, and other products best suited for your specific applications and autosampler needs, or explore the entire Thermo Scientific™ chromatography consumables portfolio.
Address Your Sample Handling Concerns
Understanding Septa
Using the right septa for your application is vital to successful assays. Using the wrong septa can compromise your results and reduce the lifespan of other lab equipment and supplies, increasing your overall costs.
Thermo Scientific Sample Handling Solutions Brochure (PDF, 13.2 MB)
Better Septa Performance
Achieve the sealing and performance characteristics of crimp top vials with the versatility and convenience of threaded vials with the patented design of Thermo Scientific™ SureStop™ vials. This innovative vial design—along with the Advanced Vial Closure System (AVCS) cap—removes subjectivity around achieving the optimal seal compression when closing a vial.
Poorly fitting closures can cause septa to push through or distort, creating the possibility of leaks and contamination.
Part of the Thermo Scientific SureSTART collection, SureStop vials and AVCS caps help mitigate error failures like cap tilt, cap deformities, dislodged septa, and septa push through, ultimately helping you reduce re-analysis costs and increase data integrity and sample throughput.
How SureStop Vials with AVCS Closures Work
See how SureStop Vials and AVCS closures combine to provide optimal sealing and protection.
Choosing the Right Septa
When choosing proper septa, there are many factors to consider: application temperature, type of solvent or sample, slit or non-slit design, and reseal ability. These factors ultimately lead to material makeup of the septa. Depending on the material chosen, you must also determine the proper tip diameter and if the septa must be able to withstand multiple injections to avoid debris.
The chart below provides a quick guide to selecting the right septa material for your experimental and application requirements.
SureSTART Collection
Need help choosing the right vial or well plate?
Non-Reactive Surfaces
Need to detect low concentrations of analytes?
Increasingly sensitive chromatography and mass spectrometry systems demand reliable vials that can routinely deliver the ultimate in purity and the lowest surface activity possible. Learn about state-of-the-art vial technology for analyzing critical analytes during low-detection-limit assays and when sample quality, reproducibility, security, and integrity are of upmost importance.
Low Particle and Low Background
Experiencing particulate background in high-sensitivity analyses?
Count on certified, high-performance SureSTART MSCERT kits for your routine mass spectrometry analyses.
- Vials and caps are tested and certified for up to 15 critical physical specifications to prevent technical or performance issues.
- Tested and certified for low background using LC-MS and GC-MS for your most challenging, sensitive applications, to ensure there are no extractables, leachables, or residual manufacturing agents present in the vial that could result in spurious chromatographic peaks and affect your results.
- Recommended for low adsorption.
- A certificate is provided with each kit.
- In addition to meeting MSCERT kit standards, MSCERT+ kits are pre-cleaned to provide the lowest ion content and particulate levels in the vials to protect sample integrity¬¬. They guarantee there is no dirt or dust from manufacturing present, which could clog your GC or LC column and affect column lifetime and system performance. Highly recommended for direct injection analysis (DIA).
Autosampler Vials and Caps for HPLC, LC-MS, GC, and GC-MS
Thermo Scientific vials and closures are available in a wide range of options to fit every HPLC, GC, and MS instrument—as well as your application and budget.
Thermo Scientific Autosampler Compatibility Chart (PDF, 192 KB)
Performance Level 1: Everyday Analysis
Verify compound presence and quantification using core detection techniques such as UV, RI, FID, or ECD.
Performance Level 2: High-Throughput Analysis
Ensure compliance in regulated environments. This range has very low metal content, extractables, and leachables. Support routine analyses using standard MS systems such as single or triple/tandem quadrupole.
Performance Level 3: High Performance
Protect valuable samples for demanding analyses. Vials contain the lowest sum of metals, extractables, and leachables. Ensure the sensitivity and selectivity of challenging analytes confidently and consistently. Support high-resolution MS systems such as Thermo Scientific™ Orbitrap™ or other time-of-flight (ToF) systems to maintain the highest levels of sample security and integrity.
